Enzyme Details

 EC Classification 1.1.1.153
 Enzyme name
(recommended)
sepiapterin reductase
 Alternative names 7,8-dihydrobiopterin:NADP+ oxidoreductase
SR
 Classification
Oxidoreductases
Acting on the CH-OH group of donors
With NAD(+) or NADP(+) as acceptor
 Catalyses reactions
NADP+ + Tetrahydrobiopterin <-> H+ + NADPH + 6-Lactoyl-5,6,7,8-tetrahydropterin
NAD+ + Acetoin <-> NADH + H+ + Dimethylglyoxal
H+ + NADPH + Methylglyoxal <-> NADP+ + Hydroxyacetone
NADP+ + 7,8-Dihydrobiopterin <-> H+ + NADPH + Sepiapterin
NADP+ + 6-Lactoyl-5,6,7,8-tetrahydropterin <-> H+ + NADPH + 6-Pyruvoyltetrahydropterin
H+ + NADPH + p-Nitrobenzaldehyde <-> NADP+ + p-Nitrobenzyl alcohol
H+ + NADPH + 9,10-Phenanthroquinone <-> NADP+ + Phenanthrene-9,10-diol
H+ + NADPH + Phenylglyoxal <-> Unknown + NADP+
H+ + NADPH + Dimethylglyoxal <-> NADP+ + Acetoin
NADP+ + Methylglyoxal <-> Unknown + H+ + NADPH
H+ + NADPH + 1-Phenyl-1,2-propanedione <-> Unknown + NADP+
H+ + NADPH + 2,4-Pentanedione <-> Unknown + NADP+
NADH + H+ + 1-Phenyl-1,2-propanedione <-> Unknown + NAD+
H+ + NADPH + Acetoin <-> NADP+ + 2,3-Butanediol
NADH + H+ + Sepiapterin <-> NAD+ + 7,8-Dihydrobiopterin
H+ + NADPH + Acetophenone <-> Unknown + NADP+
H+ + NADPH + Propiophenone <-> Unknown + NADP+
H+ + NADPH + Benzylacetone <-> Unknown + NADP+
H+ + NADPH + 1,4-Benzoquinone <-> Unknown + NADP+
H+ + NADPH + Benzil <-> Unknown + NADP+
H+ + NADPH + Menadione <-> NADP+ + Menadiol
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class 1.1.1.153



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