Enzyme Details

 EC Classification 1.1.1.37
 Enzyme name
(recommended)
malate dehydrogenase
 Alternative names (S)-malate:NAD+ oxidoreductase
malic dehydrogenase
L-malate dehydrogenase
NAD-L-malate dehydrogenase
malic acid dehydrogenase
NAD-dependent malic dehydrogenase
NAD-malate dehydrogenase
NAD-malic dehydrogenase
malate (NAD) dehydrogenase
NAD-dependent malate dehydrogenase
NAD-specific malate dehydrogenase
NAD-linked malate dehydrogenase
MDH
L-malate-NAD+ oxidoreductase
 Classification
Oxidoreductases
Acting on the CH-OH group of donors
With NAD(+) or NADP(+) as acceptor
 Catalyses reactions
NAD+ + L-Malate <-> NADH + H+ + Oxaloacetate
NADP+ + L-Malate <-> H+ + NADPH + Oxaloacetate
NAD+ + Hydroxymalonate <-> NADH + H+ + Oxomalonate
NAD+ + D-Malate <-> NADH + H+ + Oxaloacetate
L-Malate + 3-Acetylnicotinamide-NAD+ <-> H+ + Oxaloacetate + 3-Acetylnicotinamide-NADH
L-Malate + 3-Acetylpyridine-adenine dinucleotide <-> H+ + Oxaloacetate + Reduced 3-acetylpyridine-adenine dinucleotide
L-Malate + thio-NAD+ <-> H+ + Oxaloacetate + thio-NADH
Deamino-NAD+ + L-Malate <-> H+ + Oxaloacetate + Deamino-NADH
H+ + Oxaloacetate + NHDPH <-> L-Malate + NHDP+
H+ + Oxaloacetate + Deamino-NADH <-> L-Malate + Nicotinamide hypoxanthine dinucleotide
NADH + H+ + Phenylpyruvate <-> NAD+ + L-Phenyllactate
NAD+ + 3-(4-Hydroxyphenyl)lactate <-> NADH + H+ + 3-(4-Hydroxyphenyl)pyruvate
NADH + H+ + 4-Methyl-2-oxopentanoate <-> NAD+ + 2-Hydroxyisocaproate
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class 1.1.1.37



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