Enzyme Details

 EC Classification 1.1.1.85
 Enzyme name
(recommended)
3-isopropylmalate dehydrogenase
 Alternative names (2R,3S)-3-isopropylmalate:NAD+ oxidoreductase
beta-isopropylmalic enzyme
beta-isopropylmalate dehydrogenase
threo-Ds-3-isopropylmalate dehydrogenase
3-carboxy-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase
 Classification
Oxidoreductases
Acting on the CH-OH group of donors
With NAD(+) or NADP(+) as acceptor
 Catalyses reactions
NAD+ + 3-Isopropylmalate <-> NADH + H+ + 3-Carboxy-4-methyl-2-oxopentanoate
NAD+ + 3-Isopropylmalate <-> NADH + H+ + CO2 + 4-Methyl-2-oxopentanoate
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class 1.1.1.85



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