Enzyme Details

 EC Classification 3.5.1.1
 Enzyme name
(recommended)
asparaginase
 Alternative names L-asparagine amidohydrolase
asparaginase II
L-asparaginase
colaspase
elspar
leunase
crasnitin
alpha-asparaginase
 Classification
Hydrolases
Acting on carbon-nitrogen bonds, other than peptide bonds
In linear amides
 Catalyses reactions
H2O + L-Asparagine <-> L-Aspartate + NH3
L-Asparagine + Hydroxylamine <-> NH3 + L-Aspartylhydroxamate
H2O + Amide <-> NH3 + Carboxylate
H2O + L-Aspartyl-beta-hydroxamate <-> L-Aspartate + Hydroxylamine
H2O + D-Asparagine <-> NH3 + D-Aspartate
H2O + N-Benzyloxycarbonyl-L-asparagine <-> NH3 + N-Benzyloxycarbonyl-L-aspartate
H2O + N-Carbamyl-L-asparagine <-> NH3 + N-Carbamyl-L-aspartate
H2O + N-Acetyl-L-asparagine <-> NH3 + N-Acetyl-L-aspartate
H2O + Glycyl-L-asparagine <-> NH3 + Glycyl-L-aspartate
H2O + Glycyl-D-asparagine <-> NH3 + Glycyl-D-aspartate
H2O + L-Isoleucyl-L-asparagine <-> NH3 + L-Isoleucyl-L-aspartate
H2O + L-Valyl-L-asparagine <-> NH3 + L-Valyl-L-aspartate
H2O + D-Aspartyl-beta-hydroxamate <-> Hydroxylamine + D-Aspartate
Hydroxylamine + N-Acetyl-L-asparagine <-> NH3 + N-Acetyl-L-aspartylhydroxamate
H2O + L-Methionyl-L-asparagine <-> NH3 + L-Methionyl-L-aspartate
H2O + L-Aspartic acid beta-(7-amido-4-methylcoumarin) <-> L-Aspartate + NH2Mec
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class 3.5.1.1



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