Pathway Details

 Recommended name Citrate cycle (TCA cycle)
 Alternative names
Krebs cycle
TCA cycle
Citric acid cycle
 Reactions
Coenzyme A + Citrate <-> H2O + Acetyl-CoA + Oxaloacetate
NAD+ + Isocitrate <-> NADH + H+ + CO2 + 2-Oxoglutarate
Oxalosuccinate <-> CO2 + 2-Oxoglutarate
Citrate <-> H2O + cis-Aconitate
Coenzyme A + GTP + Succinate <-> Phosphate + GDP + Succinyl-CoA
Citrate <-> Acetate + Oxaloacetate
Coenzyme A + ITP + Succinate <-> Phosphate + IDP + Succinyl-CoA
ATP + Coenzyme A + Citrate <-> ADP + Phosphate + (3S)-Citryl-CoA
CO2 + Succinyl-CoA + Reduced ferredoxin <-> Coenzyme A + 2-Oxoglutarate + Oxidized ferredoxin
ATP + Coenzyme A + Succinate <-> ADP + Phosphate + Succinyl-CoA
NADP+ + Isocitrate <-> H+ + NADPH + Oxalosuccinate
NAD+ + Dihydrolipoamide <-> NADH + H+ + Lipoamide
Dihydrolipoamide + Succinyl-CoA <-> Coenzyme A + S-Succinyldihydrolipoamide
ATP + Coenzyme A + Citrate <-> ADP + Phosphate + Acetyl-CoA + Oxaloacetate
(3S)-Citryl-CoA <-> Acetyl-CoA + Oxaloacetate
NADP+ + L-Malate <-> Pyruvate + H+ + NADPH + CO2
Succinate + Acceptor <-> Fumarate + Reduced acceptor
Citrate <-> Isocitrate
NAD+ + L-Malate <-> NADH + H+ + Oxaloacetate
Isocitrate <-> H2O + cis-Aconitate
Succinate + Ubiquinone <-> Fumarate + Ubiquinol
ATP + Oxaloacetate <-> Phosphoenolpyruvate + ADP + CO2
Pyruvate + ATP + Hydrogencarbonate <-> ADP + Phosphate + Oxaloacetate
L-Malate <-> H2O + Fumarate
H2O + Succinyl-CoA <-> Coenzyme A + Succinate
Thiamine diphosphate + 2-Oxoglutarate <-> CO2 + 3-Carboxy-1-hydroxypropyl-ThPP
CO2 + 2-(alpha-Hydroxyethyl)thiamine diphosphate <-> Pyruvate + Thiamine diphosphate
NADP+ + Isocitrate <-> H+ + NADPH + CO2 + 2-Oxoglutarate
Acetyl-CoA + Citrate <-> Acetate + (3S)-Citryl-CoA
NAD+ + L-Malate <-> Pyruvate + NADH + H+ + CO2
ITP + Oxaloacetate <-> Phosphoenolpyruvate + CO2 + IDP
Lipoamide + 3-Carboxy-1-hydroxypropyl-ThPP <-> Thiamine diphosphate + S-Succinyldihydrolipoamide
GTP + Oxaloacetate <-> Phosphoenolpyruvate + CO2 + GDP
 Classification
Carbohydrate Metabolism
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